Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27616829 | 0.88 | ALDH1A1 (0.48) | ALDH1A1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL25788052 | 0.87 | ALDH1A1 (0.67) | ALDH1A1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL4602778 | 0.87 | ALDH1A1 (0.67) | ALDH1A1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL8425121 | 0.87 | ALDH1A1 (0.67) | ALDH1A1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL5981245 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL3716464 | 0.87 | ALDH1A1 (0.67) | ALDH1A1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL15263303 | 0.86 | KDM4E (0.58) | ALDH1A1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL17309756 | 0.86 | KDM4E (0.58) | ALDH1A1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL5453802 | 0.86 | KDM4E (0.58) | ALDH1A1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL2374608 | 0.86 | KDM4E (0.58) | ALDH1A1KDM4EKMT2AMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434178-A | ORGANOALUMINUM CHLORIDE COMPOUNDS | HOFFMANN-LA ROCHE, INC. (US) | 1984-02-28 | — | — | US | disclosed |