SCHEMBL1104427

SCHEMBL1104427

CCOC(=O)c1ccc2c(c1)nc(S)n2C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 6/20 0.52
SIRT1 Q96EB6 5/20 0.52
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
PDE2A O00408 1/20 0.51
MAPT P10636 3/20 0.50
NLRP3 Q96P20 1/20 0.50
KDM4E B2RXH2 2/20 0.49
NPSR1 Q6W5P4 2/20 0.48
ALDH1A1 P00352 3/20 0.47
HPGD P15428 3/20 0.47
PTGER4 P35408 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 2/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14800136 0.86 KDM4E (0.58) SIRT2SIRT1NPC1RAB9AMEN1
SCHEMBL8253380 0.84 SIRT2 (0.52) SIRT2SIRT1NPC1RAB9AMEN1
SCHEMBL28382487 0.82 NPC1 (0.56) SIRT2SIRT1NPC1RAB9AMEN1
SCHEMBL12394782 0.80 NPC1 (0.52) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL14696899 0.79 NPC1 (0.80) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL14800591 0.79 ALDH1A1 (0.48) SIRT2SIRT1NPC1RAB9AMEN1
SCHEMBL14800592 0.79 NPC1 (0.53) SIRT2SIRT1NPC1RAB9AMEN1
SCHEMBL1250669 0.78 SIRT2 (0.52) SIRT2SIRT1NPC1RAB9AMEN1
SCHEMBL14800064 0.77 KDM4E (0.80) SIRT2SIRT1NPC1RAB9AMEN1
SCHEMBL8336544 0.76 MAPT (0.51) SIRT2SIRT1NPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8168370-B2 Photosensitive composition which included photopolymerization initiator; graft polymer binder FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 US disclosed
US-7923197-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-04-12 US disclosed
US-7811742-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-10-12 US disclosed
US-7811743-B2 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-10-12 US disclosed
US-7713681-B2 Method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2010-05-11 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100075251-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20080261153-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
US-20080241739-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080160451-A1 METHOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20070287098-A1 MEHTOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2007-12-13 US disclosed
US-20070231745-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070212641-A1 Lithographic printing plate precursor and method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed