Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1701244 | 0.78 | SMN1; SMN2 (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL2750728 | 0.78 | BACE1 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL19233647 | 0.77 | HTR3E (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6487934 | 0.74 | HTR3E (0.40) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6489159 | 0.74 | HTR3E (0.40) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6491453 | 0.74 | GRM2 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL12045424 | 0.74 | BACE1 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL13008655 | 0.74 | TLR8 (0.47) | KMT2A | |
| SCHEMBL18306496 | 0.74 | GRM2 (0.44) | NPC1RAB9AGRM2L3MBTL1 | |
| SCHEMBL19851084 | 0.73 | KMT2A (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10399978-B2 | Imidazopyridine thioglycolic acid derivatives as potent inhibitors of human urate transporter 1 | SHANDONG UNIVERSITY (CN) | 2019-09-03 | — | — | US | disclosed |
| US-20190225606-A1 | Novel Imidazopyridine Thioglycolic Acid Derivatives as Potent Inhibitors of Human Urate Transporter 1 | SHANDONG UNIVERSITY (CN) | 2019-07-25 | — | — | US | disclosed |
| US-20120295204-A1 | PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR | FUJIFILM CORPORATION (JP) | 2012-11-22 | — | — | US | disclosed |
| US-8257913-B2 | Processing method of lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2012-09-04 | — | — | US | disclosed |
| US-8168370-B2 | Photosensitive composition which included photopolymerization initiator; graft polymer binder | FUJIFILM CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8151705-B2 | Method of preparing lithographic printing plate | FUJIFILM CORPORATION (JP) | 2012-04-10 | — | — | US | disclosed |
| US-7985535-B2 | Image-forming method and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2011-07-26 | — | — | US | disclosed |
| US-20110168044-A1 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110091814-A1 | PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| US-7923197-B2 | Lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20080261153-A1 | PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |
| US-20080241739-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |
| US-20080160451-A1 | METHOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20070287098-A1 | MEHTOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2007-12-13 | — | — | US | disclosed |
| US-20070231745-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070212641-A1 | Lithographic printing plate precursor and method for preparation of lithographic printing plate | FUJIFILM CORPORATION (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070207411-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2007-09-06 | — | — | US | disclosed |
| US-20070184387-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070128550-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2007-06-07 | — | — | US | disclosed |
| US-20070020563-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225606-A1 | Novel Imidazopyridine Thioglycolic Acid Derivatives as Potent Inhibitors of Human Urate Transporter 1 | SLC29A1, SLC28A1, SLC5A1 | HTR3E 4468/4885HTR3B 4092/4885HTR3A 3578/4885 |
| US-10399978-B2 | Imidazopyridine thioglycolic acid derivatives as potent inhibitors of human urate transporter 1 | SLC29A1, SLC28A1, SLC5A1 | HTR3E 4248/4885HTR3B 3811/4885HTR3A 3205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.