Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047878 | 1.00 | KMT2A (0.45) | KMT2AOPRL1ACE | |
| SCHEMBL11050571 | 1.00 | KMT2A (0.45) | KMT2AOPRL1ACE | |
| SCHEMBL11051574 | 0.89 | OPRL1 (0.40) | OPRL1ACE | |
| SCHEMBL11052936 | 0.84 | ACE (0.42) | OPRL1ACE | |
| SCHEMBL11049196 | 0.82 | KMT2A (0.55) | KMT2AACE | |
| SCHEMBL11047709 | 0.82 | KMT2A (0.55) | KMT2AACE | |
| SCHEMBL11046949 | 0.82 | KMT2A (0.55) | KMT2AACE | |
| SCHEMBL11047662 | 0.81 | ACE (0.43) | KMT2AOPRL1ACE | |
| SCHEMBL11049755 | 0.81 | KMT2A (0.54) | KMT2AACE | |
| SCHEMBL11046959 | 0.81 | KMT2A (0.54) | KMT2AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461896-A | 1-[Acylthio) and (mercapto)-1-oxoalkyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acids | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1984-07-24 | — | — | US | disclosed |