Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047878 | 0.89 | KMT2A (0.45) | OPRL1ACE | |
| SCHEMBL11044573 | 0.89 | KMT2A (0.45) | OPRL1ACE | |
| SCHEMBL11050571 | 0.89 | KMT2A (0.45) | OPRL1ACE | |
| SCHEMBL11046009 | 0.88 | MEN1 (0.36) | — | |
| SCHEMBL11052123 | 0.88 | MEN1 (0.32) | ACE | |
| SCHEMBL11045824 | 0.88 | MEN1 (0.36) | OPRL1ACECHRM2CHRM4CHRM1 | |
| SCHEMBL11052936 | 0.85 | ACE (0.42) | OPRL1ACECHRM2CHRM4CHRM1 | |
| SCHEMBL11047662 | 0.83 | ACE (0.43) | OPRL1ACECHRM2CHRM4CHRM1 | |
| SCHEMBL11043199 | 0.81 | ACE (0.55) | ACE | |
| SCHEMBL11047965 | 0.81 | ACE (0.55) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461896-A | 1-[Acylthio) and (mercapto)-1-oxoalkyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acids | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1984-07-24 | — | — | US | disclosed |