Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.57 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10392938 | 0.93 | GRIK1 (0.64) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL28858621 | 0.93 | GRIK1 (0.64) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL25343299 | 0.91 | GRIK1 (0.66) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL9224299 | 0.88 | GRIK1 (0.62) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL3487181 | 0.85 | FFAR1 (0.63) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL2229707 | 0.85 | CHRM1 (0.58) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL19031904 | 0.85 | FFAR1 (0.63) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL7711571 | 0.84 | FFAR1 (0.61) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL7181482 | 0.84 | FFAR1 (0.61) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL8148123 | 0.84 | FFAR1 (0.61) | GRIK1GRIK2SLC1A2SLC1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447440-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-08 | — | — | US | disclosed |