Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.62 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.62 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10392938 | 0.95 | GRIK1 (0.64) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL25343299 | 0.93 | GRIK1 (0.66) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL28858621 | 0.91 | GRIK1 (0.64) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL4843975 | 0.89 | GRIK1 (0.75) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL11044598 | 0.88 | GRIK1 (0.57) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL11596151 | 0.87 | GRIK1 (0.64) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL11598522 | 0.87 | GRIK1 (0.64) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL11599361 | 0.87 | GRIK1 (0.64) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL11599132 | 0.87 | GRIK1 (0.64) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL8666858 | 0.87 | GRIK1 (0.72) | GRIK1GRIK2SLC1A2SLC1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387000-B1 | Medicament for the treatment of thrombus, inflammation and high blood pressure | SUNTORY LTD (JP) | 1995-05-24 | — | — | EP | disclosed |
| US-5336496-A | Administering sesame oil or sesame seed extract | SUNTORY LIMITED (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0387000-A2 | Medicament for the treatment of thrombus, inflammation and high blood pressure | SUNTORY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |