Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.67 |
| ▸ | CASP3 | P42574 | 3/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.67 |
| ▸ | SMARCA2 | P51531 | 6/20 | 0.66 |
| ▸ | SMARCA4 | P51532 | 5/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22125270 | 0.86 | POLB (0.66) | POLBMEN1KMT2ASMARCA2SMARCA4 | |
| SCHEMBL9410906 | 0.86 | SMARCA2 (0.68) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11045984 | 0.86 | SMARCA2 (0.63) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9599834 | 0.86 | SMARCA2 (0.86) | MEN1KMT2ANPC1RAB9ASMARCA2 | |
| SCHEMBL119685 | 0.84 | SMARCA2 (0.79) | MEN1KMT2ANPC1RAB9ASMARCA2 | |
| SCHEMBL11046852 | 0.84 | MEN1 (0.72) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23831595 | 0.84 | SMARCA2 (0.57) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL30105047 | 0.84 | SMARCA2 (0.57) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23831748 | 0.83 | SMARCA2 (0.60) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL22125318 | 0.83 | SMARCA2 (0.62) | POLBMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4526780-A | Active ingredient and absorbent clays, starches, cellulose, volatile silicone gelatinized clay, bentonite gel | COLGATE-PALMOLIVE COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| US-RE31550-E | N-(2-Chloro-4-pyridyl) ureas | Shudo, Koichi (JP) | 1984-04-10 | — | — | US | disclosed |
| US-4193788-A | N-(2-Chloro-4-pyridyl)ureas | ISOGAI YO (JP) | 1980-03-18 | — | — | US | disclosed |