SCHEMBL23831748

SCHEMBL23831748

O=C(Nc1ccnc(Cl)c1)Nc1ccccc1CO

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMARCA2 P51531 9/20 0.60
SMARCA4 P51532 8/20 0.60
TRPV1 Q8NER1 3/20 0.58
POLB P06746 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
CASP3 P42574 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
MAPT P10636 1/20 0.46
CNR1 P21554 1/20 0.45
MALT1 Q9UDY8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23831594 0.90 TRPV1 (0.60) SMARCA2SMARCA4TRPV1POLBMEN1
SCHEMBL23831732 0.86 SMARCA2 (0.58) SMARCA2SMARCA4TRPV1MEN1KMT2A
SCHEMBL30104987 0.86 SMARCA2 (0.58) SMARCA2SMARCA4TRPV1MEN1KMT2A
SCHEMBL23831653 0.85 S1PR2 (0.60) TRPV1POLBMEN1KMT2ANPC1
SCHEMBL30104879 0.85 S1PR2 (0.60) TRPV1POLBMEN1KMT2ANPC1
SCHEMBL23831643 0.84 TRPV1 (0.55) SMARCA2SMARCA4TRPV1POLBMEN1
SCHEMBL23831582 0.84 TRPV1 (0.52) SMARCA2SMARCA4TRPV1POLBMEN1
SCHEMBL23831709 0.84 SMARCA2 (0.56) SMARCA2SMARCA4TRPV1POLBMEN1
SCHEMBL30105089 0.84 SMARCA2 (0.56) SMARCA2SMARCA4TRPV1MEN1KMT2A
SCHEMBL30105045 0.84 SMARCA2 (0.56) SMARCA2SMARCA4TRPV1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121415-B1 INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES UNIV PALACKEHO (CZ) 2024-02-07 EP disclosed
EP-4121415-A1 INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES Univerzita Palackého v Olomouci (CZ) 2023-01-25 EP disclosed
WO-2021185391-A1 INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2021-09-23 WO disclosed