Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1272898 | 0.93 | CALM1 (0.56) | CALM1IGF1RALOX15ALOX5TAAR1 | |
| SCHEMBL692698 | 0.85 | TAAR1 (0.55) | CALM1ALOX15TAAR1F2RL1MAOB | |
| SCHEMBL10571532 | 0.84 | CALM1 (0.69) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL9509173 | 0.84 | CALM1 (0.69) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL17400406 | 0.84 | CALM1 (0.69) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL11007798 | 0.84 | CALM1 (0.69) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL4254058 | 0.82 | CALM1 (0.72) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL11193661 | 0.81 | POLB (0.46) | POLB | |
| SCHEMBL5044882 | 0.80 | CALM1 (0.55) | CALM1IGF1RALOX15TDP1L3MBTL1 | |
| SCHEMBL18244820 | 0.80 | CALM1 (0.55) | CALM1IGF1RALOX15TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |