Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PYGL | P06737 | 11/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4B | O94953 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537925 | 0.84 | ALDH1A1 (0.47) | ALDH1A1PYGLGRIK1GRIK2GUSB | |
| SCHEMBL5537927 | 0.84 | ALDH1A1 (0.47) | ALDH1A1PYGLGRIK1GRIK2GUSB | |
| SCHEMBL5539348 | 0.83 | ALDH1A1 (0.46) | ALDH1A1PYGLGRIK1GRIK2GUSB | |
| SCHEMBL5539355 | 0.83 | ALDH1A1 (0.46) | ALDH1A1PYGLGRIK1GRIK2GUSB | |
| SCHEMBL2089138 | 0.82 | ALDH1A1 (0.57) | ALDH1A1PYGLGRIK1GRIK2GUSB | |
| SCHEMBL2096810 | 0.82 | ALDH1A1 (0.57) | ALDH1A1PYGLGRIK1GRIK2GUSB | |
| SCHEMBL8099815 | 0.81 | CHAT (0.45) | ALDH1A1PYGLGRIK1GRIK2CHAT | |
| SCHEMBL28015751 | 0.81 | CHAT (0.45) | ALDH1A1PYGLGRIK1GRIK2CHAT | |
| SCHEMBL5540658 | 0.80 | ALDH1A1 (0.50) | ALDH1A1PYGLGRIK1GRIK2GUSB | |
| SCHEMBL5540657 | 0.80 | ALDH1A1 (0.50) | ALDH1A1PYGLGRIK1GRIK2GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |