Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049002 | 0.94 | GAA (0.56) | GAACDK1MAPTTP53GLA | |
| SCHEMBL11045419 | 0.90 | LMNA (0.46) | TSHRGAAMAPTKDM4ENPC1 | |
| SCHEMBL11125345 | 0.90 | TSHR (0.52) | TSHRSMN1; SMN2GAACDK1MAPT | |
| SCHEMBL11119679 | 0.89 | SMN1; SMN2 (0.47) | TSHRSMN1; SMN2GAACDK1MAPT | |
| SCHEMBL11050733 | 0.89 | TSHR (0.51) | TSHRSMN1; SMN2GAACDK1MAPT | |
| SCHEMBL10801614 | 0.88 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2GAACDK1MAPT | |
| SCHEMBL11049312 | 0.88 | SMN1; SMN2 (0.53) | TSHRSMN1; SMN2GAACDK1MAPT | |
| SCHEMBL11045303 | 0.87 | TSHR (0.49) | TSHRSMN1; SMN2GAACDK1MAPT | |
| SCHEMBL11046113 | 0.86 | GAA (0.50) | TSHRSMN1; SMN2GAACDK1MAPT | |
| SCHEMBL10733365 | 0.85 | GAA (0.53) | TSHRSMN1; SMN2GAACDK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044209-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | claimed |
| US-4348220-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | claimed |
| EP-0044209-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-20 | — | — | EP | claimed |
| EP-0044209-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | disclosed |
| US-4424377-A | HERBICIDES | E. I. DU PONT DE NEMOURS & CO. (US) | 1984-01-03 | — | — | US | disclosed |
| US-4348220-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0044209-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-20 | — | — | EP | disclosed |