Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044925 | 1.00 | KDM4E (0.58) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL1137220 | 0.81 | AKR1C3 (0.66) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL1137218 | 0.81 | AKR1C3 (0.66) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL16029355 | 0.81 | KDM4E (0.62) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL30513704 | 0.81 | KDM4E (0.62) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL16029354 | 0.81 | KDM4E (0.62) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL16029353 | 0.81 | KDM4E (0.62) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL6381221 | 0.81 | KDM4E (0.62) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL1804114 | 0.80 | AKR1C3 (0.61) | KDM4EFBP1MEN1KMT2AAKR1C3 | |
| SCHEMBL1804115 | 0.80 | AKR1C3 (0.61) | KDM4EFBP1MEN1KMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028063-B1 | PHENOL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1984-06-13 | — | — | EP | disclosed |
| EP-0028063-A1 | Phenol derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1981-05-06 | — | — | EP | disclosed |