Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16029354 | 1.00 | KDM4E (0.62) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL30513704 | 1.00 | KDM4E (0.62) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL16029353 | 1.00 | KDM4E (0.62) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL6381221 | 0.84 | KDM4E (0.62) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| Phenol SCHEMBL15014256 | 0.83 | AKR1C3 (0.52) | KDM4EMMP1MMP2MMP9CA12 | |
| SCHEMBL10783473 | 0.83 | KDM4E (0.53) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL12553419 | 0.81 | KDM4E (0.58) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL11044928 | 0.81 | KDM4E (0.58) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL1137220 | 0.81 | AKR1C3 (0.66) | KDM4ECCNB2CDK1CDK4CCNB1 | |
| SCHEMBL11044925 | 0.81 | KDM4E (0.58) | KDM4ECCNB2CDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496694-B | Supermolecular modified organic silicon marine antifouling paint and preparation method thereof | 常熟理工学院 | 2024-05-03 | — | — | CN | claimed |
| CN-116496694-A | Supermolecular modified organic silicon marine antifouling paint and preparation method thereof | 常熟理工学院 | 2023-07-28 | — | — | CN | claimed |
| CN-116496694-B | Supermolecular modified organic silicon marine antifouling paint and preparation method thereof | 常熟理工学院 | 2024-05-03 | — | — | CN | disclosed |
| CN-116496694-A | Supermolecular modified organic silicon marine antifouling paint and preparation method thereof | 常熟理工学院 | 2023-07-28 | — | — | CN | disclosed |
| US-8993762-B2 | Total synthesis of thaxtomin A analogues and their intermediates | MARRONE BIO INNOVATIONS, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| WO-2014149171-A1 | TOTAL SYNTHESIS OF THAXTOMIN A ANALOGUES AND THEIR INTERMEDIATES | MARRONE BIO INNOVATIONS, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140275541-A1 | TOTAL SYNTHESIS OF THAXTOMIN A ANALOGUES AND THEIR INTERMEDIATES | PRO FARM GROUP, INC. | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275541-A1 | TOTAL SYNTHESIS OF THAXTOMIN A ANALOGUES AND THEIR INTERMEDIATES | HAAO, GART, TDO2 | KDM4E 2083/4885CCNB2 3376/4885CDK1 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.