SCHEMBL11045185

SCHEMBL11045185

ClC(Cl)c1c(Br)cccc1Br

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
ALDH1A1 P00352 2/20 0.33
PDPK1 O15530 1/20 0.31
AHR P35869 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27437420 0.85 CYP1A2 (0.36) TSHRALDH1A1PDPK1AHR
SCHEMBL28773713 0.83 ALDH1A1 (0.32) ALDH1A1AHR
SCHEMBL4086841 0.81 ALDH1A1 (0.36) ALDH1A1PDPK1AHRMAPK1
SCHEMBL6816725 0.71 PARP1 (0.35) AHR
SCHEMBL1770665 0.71 ALDH1A1 (0.33) ALDH1A1AHRMAPK1
SCHEMBL12360647 0.71 ALDH1A1 (0.39) TSHRALDH1A1AHRMAPK1
SCHEMBL28773662 0.70 IDO1 (0.31) TSHR
SCHEMBL18242188 0.69 ALDH1A1 (0.38) ALDH1A1
SCHEMBL10830794 0.69 ALDH1A1 (0.38) ALDH1A1AHR
SCHEMBL27456159 0.69 IDO1 (0.42) TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4450298-A Vapor phase catalytic hydrolysis of benzal chloride or its halogen- or trifluoromethyl-substitute to form benzaldehyde or substitute CENTRAL GLASS COMPANY, LIMITED (JP) 1984-05-22 US claimed
CN-1651142-A Catalyst component used for ethylene oligomerization, preparing process and application thereof DAQING PETROCHEMICAL BRANCH CO (CN) 2005-08-10 CN disclosed
CN-1108193-C Novel catalyst for ethylene trimerization, its preparation process and application RES INST BEIJING YANSHAN PETRO (CN) 2003-05-14 CN disclosed
CN-1256968-A Novel catalyst for ethylene trimerization, its preparation process and application RES INST BEIJING YANSHAN PETRO (CN) 2000-06-21 CN disclosed
US-4450298-A Vapor phase catalytic hydrolysis of benzal chloride or its halogen- or trifluoromethyl-substitute to form benzaldehyde or substitute CENTRAL GLASS COMPANY, LIMITED (JP) 1984-05-22 US disclosed