Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.54 |
| ▸ | MAOA | P21397 | 8/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040027 | 0.93 | MAOB (0.62) | MAOBMAOATSHRNPC1RAB9A | |
| SCHEMBL6483452 | 0.85 | MAOB (0.62) | MAOBMAOATSHRNPC1RAB9A | |
| SCHEMBL13534217 | 0.79 | MAOB (0.59) | MAOBMAOATSHRNPC1RAB9A | |
| SCHEMBL13533377 | 0.78 | MAOB (0.50) | MAOBMAOATSHRNPC1RAB9A | |
| SCHEMBL13533384 | 0.76 | MAOB (0.59) | MAOBMAOATSHRNPC1RAB9A | |
| SCHEMBL31371765 | 0.76 | RAB9A (0.48) | MAOBMAOANPC1RAB9AMAPT | |
| SCHEMBL13533366 | 0.74 | MAOB (0.57) | MAOBMAOATSHRNPC1RAB9A | |
| SCHEMBL30627668 | 0.74 | MAOB (0.62) | MAOBMAOATSHRNPC1RAB9A | |
| SCHEMBL14088714 | 0.74 | MAOB (0.62) | MAOBMAOATSHRNPC1RAB9A | |
| SCHEMBL7931197 | 0.74 | MAOB (0.45) | MAOBMAOATSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |