Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048021 | 0.82 | HRH3 (0.36) | SLC6A2SLC6A3HRH3MAPTMEN1 | |
| Fumaric Acid SCHEMBL11045460 | 0.71 | SLC6A2 (0.46) | SLC6A2SLC6A3CYP2D6CHRM2ADRA2A | |
| Fumaric Acid SCHEMBL11045472 | 0.71 | SLC6A2 (0.46) | SLC6A2SLC6A3CYP2D6CHRM2ADRA2A | |
| Oxalic Acid SCHEMBL11391218 | 0.66 | CYP2D6 (0.59) | SLC6A2SLC6A3CYP2D6CHRM2ADRA2A | |
| SCHEMBL11046245 | 0.64 | OPRK1 (0.41) | SLC6A2SLC6A3MEN1LMNAKMT2A | |
| SCHEMBL9682587 | 0.63 | DRD3 (0.69) | SLC6A2SLC6A3CYP2D6CHRM2ADRA2A | |
| SCHEMBL8625307 | 0.60 | HCAR2 (0.59) | CYP2D6MAPK1MAPTLMNAKMT2A | |
| SCHEMBL27534210 | 0.60 | HCAR2 (0.59) | CYP2D6MAPK1MAPTLMNAKMT2A | |
| SCHEMBL8625297 | 0.60 | HCAR2 (0.59) | CYP2D6MAPK1MAPTLMNAKMT2A | |
| SCHEMBL9596360 | 0.60 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM1OPRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451473-A | 3,7-Diazabicyclo [3.3.1] nonanes having anti-arrhythmic activity | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-05-29 | — | — | US | disclosed |