Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4273867 | 0.85 | CACNA2D1 (0.41) | BRD4HTTTSHRLMNAMAPT | |
| SCHEMBL10939085 | 0.85 | TSHR (0.38) | BRD4TSHRESR1PTGS1CACNA1C | |
| SCHEMBL30033057 | 0.83 | TDP1 (0.42) | LMNACHRM1ADRA1AALDH1A1KMT2A | |
| SCHEMBL11616021 | 0.83 | TDP1 (0.42) | LMNACHRM1ADRA1AALDH1A1KMT2A | |
| SCHEMBL10798581 | 0.83 | SCN4A (0.42) | HTTTSHRLMNAMAPTALDH1A1 | |
| SCHEMBL96016 | 0.83 | S1PR2 (0.38) | BRD4HTTTSHRLMNAMAPT | |
| SCHEMBL10799696 | 0.79 | ACP3 (0.48) | TSHRLMNAESR1CHRM2CHRM4 | |
| SCHEMBL29486495 | 0.78 | TYR (0.46) | BRD4HTTTSHRLMNAMAPT | |
| SCHEMBL444327 | 0.78 | TYR (0.46) | BRD4HTTTSHRLMNAMAPT | |
| SCHEMBL23934953 | 0.77 | TACR1 (0.44) | BRD4HTTLMNAMAPTTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474993-A | TO PRODUCE BENZYL ALCOHOL OR BENZALDEHYDE | HAG GOERAN L F (SE) | 1984-10-02 | — | — | US | disclosed |
| US-4377578-A | ANTIANAPHYLACTIC AGENTS, ANTIHISTAMINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1983-03-22 | — | — | US | disclosed |
| US-4250176-A | BENZIMIDAZOLE-2-ONE, BENZOTHIAZOL-2-ONE, OR BENZOXAZOL-2-ONE SUBSTITUTIONS, ANTIANAPHALACTIC AGENTS, ANTIHISTAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1981-02-10 | — | — | US | disclosed |
| US-4200641-A | ANTIANAPHYLACTIC AGENTS, ANTIHISTAMINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1980-04-29 | — | — | US | disclosed |
| US-4161464-A | ONIUM SALT, HYDROXYL IONS | THE B. F. GOODRICH COMPANY (US) | 1979-07-17 | — | — | US | disclosed |