SCHEMBL23934953

SCHEMBL23934953

Cc1ccc(C)c(C(N)c2ccccc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 3/20 0.44
HTT P42858 2/20 0.41
BRD4 O60885 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
DPP4 P27487 2/20 0.38
F2 P00734 1/20 0.38
LMNA P02545 3/20 0.38
ESR1 P03372 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
MAPT P10636 1/20 0.38
CHRM1 P11229 1/20 0.38
KCNE1 P15382 1/20 0.38
CHRM3 P20309 1/20 0.38
PTGS1 P23219 1/20 0.38
HRH2 P25021 1/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19665100 0.98 TACR1 (0.43) TACR1HTTBRD4ALDH1A1TDP1
SCHEMBL14677066 0.85 TACR1 (0.41) TACR1HTTALDH1A1TDP1DPP4
SCHEMBL14677950 0.85 TACR1 (0.41) TACR1HTTALDH1A1TDP1DPP4
SCHEMBL14675573 0.85 TACR1 (0.41) TACR1HTTALDH1A1TDP1DPP4
Hydrochloric Acid SCHEMBL14676739 0.83 SLC6A2 (0.41) TACR1HTTALDH1A1TDP1DPP4
Hydrochloric Acid SCHEMBL17871740 0.83 SLC6A2 (0.41) TACR1HTTALDH1A1TDP1DPP4
Hydrochloric Acid SCHEMBL14676736 0.83 SLC6A2 (0.41) TACR1HTTALDH1A1TDP1DPP4
SCHEMBL95773 0.81 IDO1 (0.40) TACR1DPP4F2LMNAESR1
SCHEMBL27886161 0.81 CHRM1 (0.52) HTTALDH1A1TDP1LMNAESR1
SCHEMBL19665163 0.81 IDO1 (0.39) TACR1DPP4F2LMNAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3623865-B1 ELECTROCHROMIC DEVICE USING ORGANIC/METAL HYBRID POLYMER AND METHOD FOR PRODUCING SAME NAT INST MATERIALS SCIENCE (JP) 2021-10-20 EP disclosed