Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.61 |
| ▸ | WNT3A | P56704 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | TPMT | P51580 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1659363 | 0.91 | MAPT (0.71) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL1322947 | 0.89 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL7380780 | 0.86 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL30629388 | 0.86 | CA12 (0.65) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL4438295 | 0.86 | CA12 (0.65) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL14660404 | 0.84 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL10455919 | 0.83 | CTNNB1 (0.83) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL11599111 | 0.83 | MAPT (0.55) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL28881824 | 0.83 | MEN1 (0.71) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL29668496 | 0.83 | MEN1 (0.71) | MAPTALDH1A1SMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |