Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | HMGCR | P04035 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20558035 | 0.81 | POLB (0.47) | POLBTSHRGAAL3MBTL1TP53 | |
| SCHEMBL20768685 | 0.79 | CYP3A4 (0.48) | TSHRGAAL3MBTL1CYP3A4 | |
| SCHEMBL2821620 | 0.77 | POLB (0.44) | POLBTSHRGAAL3MBTL1TP53 | |
| SCHEMBL7173216 | 0.77 | POLB (0.44) | POLBTSHRGAAL3MBTL1TP53 | |
| SCHEMBL27687653 | 0.76 | POLB (0.47) | POLBTSHRGAAL3MBTL1TP53 | |
| SCHEMBL4453625 | 0.76 | PPARD (0.45) | POLBTSHRGAAL3MBTL1TP53 | |
| SCHEMBL3904945 | 0.75 | POLB (0.50) | POLBTSHRGAAL3MBTL1TP53 | |
| SCHEMBL4462235 | 0.75 | POLB (0.50) | POLBTSHRGAAL3MBTL1TP53 | |
| SCHEMBL7298542 | 0.74 | TSHR (0.42) | POLBTSHRGAAL3MBTL1TP53 | |
| SCHEMBL3822346 | 0.73 | POLB (0.48) | POLBTSHRGAAL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4475943-A | Herbicidal α-hydroxy phosphonates | MONSANTO COMPANY (US) | 1984-10-09 | — | — | US | disclosed |
| US-4413125-A | α-Hydroxy phosphonates | MONSANTO COMPANY (US) | 1983-11-01 | — | — | US | disclosed |