SCHEMBL4462235

SCHEMBL4462235

CCOP(=O)(OCC)C(O)O

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
TSHR P16473 2/20 0.48
GAA P10253 2/20 0.44
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PPARD Q03181 2/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HMGCR P04035 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3904945 0.83 POLB (0.50) POLBTSHRGAATP53TDP1
SCHEMBL3822346 0.81 POLB (0.48) POLBTSHRGAATP53TDP1
SCHEMBL20558035 0.79 POLB (0.47) POLBTSHRGAATP53TDP1
SCHEMBL27687653 0.79 POLB (0.47) POLBTSHRGAATP53TDP1
SCHEMBL4449824 0.79 LPAR5 (0.39) POLBGAACYP3A4HMGCR
SCHEMBL9237295 0.77 PPARD (0.46) POLBTSHRGAATP53TDP1
SCHEMBL9050380 0.77 POLB (0.46) POLBTSHRGAATP53TDP1
SCHEMBL10911354 0.77 TSHR (0.53) POLBTSHRGAATP53TDP1
SCHEMBL4449162 0.75 CYP3A4 (0.56) TSHRGAACYP3A4
SCHEMBL11045698 0.75 POLB (0.44) POLBTSHRGAATP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed