Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11179907 | 0.88 | HTT (0.36) | HTTALDH1A1GFERNPSR1TDP1 | |
| SCHEMBL11049343 | 0.85 | KDM4E (0.44) | HTTALDH1A1GFERTDP1MEN1 | |
| SCHEMBL11434260 | 0.80 | KDM4E (0.37) | HTTALDH1A1GFERTDP1MEN1 | |
| SCHEMBL24387810 | 0.75 | HTT (0.48) | HTTALDH1A1GFERNPSR1TDP1 | |
| SCHEMBL21738035 | 0.74 | HTT (0.47) | HTTALDH1A1GFERNPSR1TDP1 | |
| SCHEMBL11175159 | 0.73 | KDM4E (0.33) | LMNA | |
| SCHEMBL11179911 | 0.73 | GBA1 (0.36) | — | |
| SCHEMBL28231770 | 0.72 | HTT (0.45) | HTTALDH1A1GFERNPSR1TDP1 | |
| SCHEMBL3654698 | 0.71 | L3MBTL1 (0.47) | HTTALDH1A1GFERNPSR1TDP1 | |
| SCHEMBL18764815 | 0.71 | HTT (0.41) | HTTALDH1A1GFERNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487767-A | BACTERIOSTATS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4385181-A | CHAMICAL INTERMEDIATES FOR CEPHALOSPORINS | RHONE POULENC INDUSTRIES (FR) | 1983-05-24 | — | — | US | disclosed |
| US-4366153-A | CEPHALOSPORINS; ANTIBIOTICS; BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-12-28 | — | — | US | disclosed |
| US-4341775-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-27 | — | — | US | disclosed |