Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 13/20 | 0.69 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271001 | 0.82 | FDPS (1.00) | FDPSBTN3A1PDE3AGGPS1LMNA | |
| SCHEMBL30683242 | 0.82 | FDPS (0.71) | FDPSBTN3A1PDE3AGGPS1 | |
| SCHEMBL23197624 | 0.80 | FDPS (0.69) | FDPSBTN3A1PDE3AGGPS1 | |
| SCHEMBL10881272 | 0.80 | FDPS (0.69) | FDPSBTN3A1PDE3AGGPS1LMNA | |
| SCHEMBL10882178 | 0.80 | FDPS (0.69) | FDPSBTN3A1PDE3AGGPS1PTPN5 | |
| SCHEMBL18107090 | 0.80 | FDPS (0.96) | FDPSBTN3A1PDE3AGGPS1LMNA | |
| SCHEMBL11044425 | 0.79 | FDPS (0.62) | FDPSBTN3A1PDE3AGGPS1 | |
| SCHEMBL3846830 | 0.79 | FDPS (1.00) | FDPSBTN3A1PDE3AGGPS1 | |
| SCHEMBL12257793 | 0.78 | FDPS (0.62) | FDPSBTN3A1PDE3AGGPS1PTPN5 | |
| SCHEMBL2457891 | 0.76 | FDPS (1.00) | FDPSBTN3A1PDE3AGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473560-A | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | claimed |
| EP-0085321-A2 | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-08-10 | — | — | EP | claimed |
| US-4473560-A | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |
| EP-0085321-A2 | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-08-10 | — | — | EP | disclosed |