Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043195 | 0.94 | GAA (0.54) | GAAMEN1CYP2C9KMT2ACDK1 | |
| SCHEMBL11043153 | 0.91 | MEN1 (0.53) | GAAMEN1CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL10909263 | 0.90 | GAA (0.52) | GAAMEN1CYP2C9KMT2ATSHR | |
| SCHEMBL11045779 | 0.85 | KDM4E (0.41) | GAAMEN1CYP2C9KMT2APOLB | |
| SCHEMBL11047131 | 0.84 | GAA (0.49) | GAAKMT2ATSHRSMN1; SMN2CDK1 | |
| SCHEMBL11562116 | 0.84 | GAA (0.58) | GAAKMT2ACDK1L3MBTL1 | |
| SCHEMBL11045678 | 0.84 | MEN1 (0.41) | MEN1CYP2C9KMT2ASMN1; SMN2POLB | |
| SCHEMBL11042813 | 0.84 | KDM4E (0.39) | GAAMEN1CYP2C9KMT2AL3MBTL1 | |
| SCHEMBL11112387 | 0.81 | POLB (0.54) | GAAMEN1CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL11109018 | 0.80 | GAA (0.51) | GAAMEN1KMT2ASMN1; SMN2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460404-A | HERBICIDES PLANT GROWTH REGULATORS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0030141-B1 | HERBICIDAL UREAS AND ISOUREAS, PREPARATION, COMPOSITIONS AND USE THEREOF, INTERMEDIATES THEREFOR AND PREPARATION OF SAID INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4452627-A | HERBICIDE, PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| US-4370479-A | PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-25 | — | — | US | disclosed |
| EP-0030141-A2 | Herbicidal ureas and isoureas, preparation, compositions and use thereof, intermediates therefor and preparation of said intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | disclosed |