Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045722 | 1.00 | ACE (0.64) | ACE | |
| SCHEMBL11049197 | 0.99 | ACE (0.62) | ACE | |
| SCHEMBL11048719 | 0.89 | ACE (0.67) | ACE | |
| SCHEMBL11049193 | 0.87 | ACE (0.49) | ACE | |
| SCHEMBL10908646 | 0.86 | ACE (0.62) | ACE | |
| SCHEMBL10909502 | 0.86 | ACE (0.62) | ACE | |
| SCHEMBL11187464 | 0.83 | ACE (0.60) | ACE | |
| SCHEMBL11052960 | 0.82 | ACE (0.58) | ACE | |
| SCHEMBL11047965 | 0.81 | ACE (0.55) | ACE | |
| SCHEMBL11043199 | 0.81 | ACE (0.55) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461896-A | 1-[Acylthio) and (mercapto)-1-oxoalkyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acids | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1984-07-24 | — | — | US | disclosed |