Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405987 | 0.87 | GAA (0.42) | TNFKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL10737553 | 0.85 | TNF (0.35) | TNFPYCR1KDM4EALDH1A1P2RX7 | |
| SCHEMBL10737423 | 0.83 | TNF (0.34) | TNFPYCR1KDM4EALDH1A1P2RX7 | |
| SCHEMBL6972728 | 0.79 | ALDH1A1 (0.42) | ALDH1A1P2RX7LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL10406697 | 0.77 | HTR1D (0.41) | MAPTKMT2AHTR1DHTR1BMEN1 | |
| SCHEMBL10742584 | 0.75 | TAAR1 (0.47) | KDM4EALDH1A1MAPTLMNATP53 | |
| SCHEMBL6972732 | 0.75 | NOTUM (0.39) | ALDH1A1RAB9ANPC1HTT | |
| SCHEMBL11045854 | 0.73 | DAO (0.42) | LMNA | |
| Detomidine SCHEMBL7087060 | 0.73 | ALDH1A1 (0.35) | ALDH1A1P2RX7TP53KMT2ASLC6A2 | |
| Detomidine SCHEMBL247340 | 0.73 | ALDH1A1 (0.35) | ALDH1A1P2RX7TP53KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024829-B1 | 4-BENZYL- AND 4-BENZOYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Farmos-Yhtyma Oy (FI) | 1984-04-25 | — | — | EP | claimed |
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | claimed |
| EP-0024829-A1 | 4-Benzyl- and 4-benzoylimidazole derivatives, processes for their preparation and pharmaceutical compositions comprising the same | Farmos-Yhtyma Oy (FI) | 1981-03-11 | — | — | EP | claimed |
| EP-0024829-B1 | 4-BENZYL- AND 4-BENZOYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Farmos-Yhtyma Oy (FI) | 1984-04-25 | — | — | EP | disclosed |
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | disclosed |
| EP-0024829-A1 | 4-Benzyl- and 4-benzoylimidazole derivatives, processes for their preparation and pharmaceutical compositions comprising the same | Farmos-Yhtyma Oy (FI) | 1981-03-11 | — | — | EP | disclosed |