Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 3/20 | 0.64 |
| ▸ | ESR1 | P03372 | 2/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.51 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045887 | 1.00 | NR1I2 (0.64) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL16034188 | 0.90 | NR1I2 (0.79) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL16034186 | 0.90 | NR1I2 (0.79) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL11344928 | 0.90 | NR1I2 (0.79) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL11344926 | 0.90 | NR1I2 (0.79) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL9510176 | 0.89 | NR1I2 (0.65) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL11041820 | 0.89 | NR1I2 (0.65) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL11040724 | 0.88 | NR1I2 (0.62) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL11040722 | 0.88 | NR1I2 (0.62) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL10930657 | 0.88 | NR1I2 (0.64) | NR1I2ESR1PGRPPARGTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027599-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-03 | — | — | EP | disclosed |
| US-4425340-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| US-4390534-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| EP-0027599-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-29 | — | — | EP | disclosed |