Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 4/20 | 0.65 |
| ▸ | ESR1 | P03372 | 2/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | APEX1 | P27695 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041820 | 1.00 | NR1I2 (0.65) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL11145207 | 0.94 | NR1I2 (0.57) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL11145202 | 0.94 | NR1I2 (0.57) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL11250454 | 0.93 | NR1I2 (0.57) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL11250467 | 0.93 | NR1I2 (0.57) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL10930664 | 0.93 | NR1I2 (0.64) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL10930657 | 0.93 | NR1I2 (0.64) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL11059582 | 0.93 | ADRA1A (0.58) | NR1I2ESR1PGRPPARGTDP1 | |
| SCHEMBL11055622 | 0.92 | NR1I2 (0.56) | NR1I2ESR1PGRPPARGTDP1 | |
| Sulfuric Acid SCHEMBL9513412 | 0.92 | NR1I2 (0.56) | NR1I2ESR1PGRPPARGTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338313-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-06 | — | — | US | claimed |
| EP-0027599-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-29 | — | — | EP | claimed |
| EP-0303223-B1 | Water-soluble antibiotic composition and water-soluble salts of new cephem compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5104866-A | WATER-SOLUBLE ANTIBIOTIC COMPOSITION AND WATER-SOLUBLE SALTS OF CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0303223-A2 | Water-soluble antibiotic composition and water-soluble salts of new cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |
| EP-0027599-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-03 | — | — | EP | disclosed |
| US-4408042-A | BACTERICIDAL CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| US-4338313-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-06 | — | — | US | disclosed |
| US-4332800-A | BACTERICIDES CONTAINING 7-AMINOTHIADIAZOLE GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| EP-0027599-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-29 | — | — | EP | disclosed |