Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045546 | 0.89 | GAA (0.54) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL11041517 | 0.83 | GAA (0.55) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL10509250 | 0.82 | CDK1 (0.70) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL3688328 | 0.80 | CDK1 (0.61) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL1537350 | 0.80 | CDK1 (0.67) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL7708124 | 0.80 | CDK1 (0.54) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL9718364 | 0.79 | CDK1 (0.63) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL9718299 | 0.79 | CDK1 (0.63) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL11042157 | 0.79 | MAPT (0.48) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL11564241 | 0.79 | GAA (0.59) | CDK1GAAMAPTTP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460404-A | HERBICIDES PLANT GROWTH REGULATORS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0030141-B1 | HERBICIDAL UREAS AND ISOUREAS, PREPARATION, COMPOSITIONS AND USE THEREOF, INTERMEDIATES THEREFOR AND PREPARATION OF SAID INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4452627-A | HERBICIDE, PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| US-4370479-A | PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-25 | — | — | US | disclosed |
| EP-0030141-A2 | Herbicidal ureas and isoureas, preparation, compositions and use thereof, intermediates therefor and preparation of said intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | disclosed |