Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537350 | 0.81 | CDK1 (0.67) | CDK1GAAKMT2AMAPTTP53 | |
| SCHEMBL4621134 | 0.80 | CDK1 (0.68) | CDK1GAAHPGDMAPTPOLB | |
| SCHEMBL11562116 | 0.80 | GAA (0.58) | CDK1GAAKMT2AMAPTTP53 | |
| SCHEMBL10509250 | 0.80 | CDK1 (0.70) | CDK1GAAKMT2AMAPTTP53 | |
| SCHEMBL11045944 | 0.80 | CDK1 (0.59) | CDK1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11043195 | 0.79 | GAA (0.54) | CDK1GAAMEN1KMT2ACYP2C9 | |
| Nicosulfuron SCHEMBL8536419 | 0.77 | CDK1 (0.59) | CDK1GAAMEN1KMT2ASMN1; SMN2 | |
| Nicosulfuron SCHEMBL29440408 | 0.77 | CDK1 (0.59) | CDK1GAAMEN1KMT2ASMN1; SMN2 | |
| Nicosulfuron SCHEMBL22938 | 0.77 | CDK1 (0.59) | CDK1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10984018 | 0.77 | GAA (0.60) | CDK1GAAKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365739-B1 | REACTION OF AMINOPYRAMIDINE WITH PHOSGENE TO FORM ISOCYANATO PYRIMIDINE | HOECHST SCHERING AGREVO GMBH (DE) | 2002-04-02 | — | — | US | disclosed |