Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10951614 | 0.89 | MEN1 (0.57) | HCAR2KMT2AMEN1LMNAHTT | |
| SCHEMBL14349697 | 0.83 | HCAR2 (0.64) | HCAR2KMT2AMEN1LMNANPSR1 | |
| SCHEMBL10946494 | 0.82 | MEN1 (0.80) | KMT2AMEN1LMNAHTTNPSR1 | |
| SCHEMBL8689332 | 0.81 | HCAR2 (1.00) | HCAR2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL8688582 | 0.79 | HCAR2 (0.68) | HCAR2KMT2AMEN1LMNAHTT | |
| SCHEMBL27549736 | 0.79 | HCAR2 (0.80) | HCAR2GAAKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL10954626 | 0.79 | LMNA (0.86) | KMT2AMEN1LMNAHTTNPSR1 | |
| SCHEMBL14338416 | 0.76 | F10 (0.77) | HCAR2KMT2AMEN1LMNAHTT | |
| SCHEMBL14340800 | 0.76 | HCAR2 (0.81) | HCAR2GAAKDM4E | |
| SCHEMBL12861472 | 0.76 | KMT2A (0.54) | HCAR2KMT2AMEN1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124791-A1 | Aralkanamidophenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1984-11-14 | — | — | EP | disclosed |