Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.75 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.75 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9599834 | 0.88 | SMARCA2 (0.86) | SMARCA2SMARCA4RAB9ANPC1KMT2A | |
| SCHEMBL11047103 | 0.87 | SMARCA2 (0.79) | SMARCA2SMARCA4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22125195 | 0.86 | SMARCA2 (1.00) | SMARCA2SMARCA4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22125200 | 0.85 | SMARCA2 (1.00) | SMARCA2SMARCA4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22125259 | 0.85 | SMARCA2 (0.71) | SMARCA2SMARCA4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11045048 | 0.85 | SMARCA2 (0.71) | SMARCA2SMARCA4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22125204 | 0.84 | SMARCA2 (0.74) | SMARCA2SMARCA4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22125272 | 0.84 | SMARCA2 (0.66) | SMARCA2SMARCA4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL119685 | 0.84 | SMARCA2 (0.79) | SMARCA2SMARCA4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22125519 | 0.84 | SMARCA2 (0.69) | SMARCA2SMARCA4RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | claimed |
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |
| US-RE31550-E | N-(2-Chloro-4-pyridyl) ureas | Shudo, Koichi (JP) | 1984-04-10 | — | — | US | disclosed |
| US-4193788-A | N-(2-Chloro-4-pyridyl)ureas | ISOGAI YO (JP) | 1980-03-18 | — | — | US | disclosed |