Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 8/20 | 0.79 |
| ▸ | SMARCA4 | P51532 | 7/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | CNR1 | P21554 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9599834 | 0.91 | SMARCA2 (0.86) | SMARCA2SMARCA4MEN1KMT2ACNR1 | |
| SCHEMBL22125200 | 0.88 | SMARCA2 (1.00) | SMARCA2SMARCA4MEN1KMT2ALMNA | |
| SCHEMBL22125204 | 0.87 | SMARCA2 (0.74) | SMARCA2SMARCA4MEN1KMT2ACNR1 | |
| SCHEMBL11046021 | 0.87 | SMARCA2 (0.75) | SMARCA2SMARCA4MEN1KMT2ACNR1 | |
| SCHEMBL119685 | 0.87 | SMARCA2 (0.79) | SMARCA2SMARCA4MEN1KMT2ACNR1 | |
| SCHEMBL27968802 | 0.86 | SMARCA2 (0.72) | SMARCA2SMARCA4MEN1KMT2ACNR1 | |
| SCHEMBL22125125 | 0.85 | SMARCA2 (0.71) | SMARCA2SMARCA4MEN1KMT2ANPC1 | |
| SCHEMBL22125520 | 0.85 | SMARCA2 (0.76) | SMARCA2SMARCA4MEN1KMT2ACNR1 | |
| SCHEMBL22125235 | 0.84 | MEN1 (0.74) | SMARCA2SMARCA4MEN1KMT2ANPC1 | |
| SCHEMBL9410880 | 0.84 | MEN1 (0.72) | SMARCA2SMARCA4MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | claimed |
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |
| US-RE31550-E | N-(2-Chloro-4-pyridyl) ureas | Shudo, Koichi (JP) | 1984-04-10 | — | — | US | disclosed |
| US-4193788-A | N-(2-Chloro-4-pyridyl)ureas | ISOGAI YO (JP) | 1980-03-18 | — | — | US | disclosed |