SCHEMBL11046076

SCHEMBL11046076

COC(=O)[C@@H]1[C@H](CC(Cl)(Cl)C(F)(F)F)C1(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
POLA1 P09884 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3366011 1.00 GAA (0.33) GAAPOLA1
Cyclopropane Carboxylic Acid SCHEMBL3365885 0.89 GAA (0.31) GAA
SCHEMBL295631 0.84 POLA1 (0.32) POLA1
SCHEMBL10988592 0.84 LMNA (0.43)
SCHEMBL809280 0.83 POLA1 (0.31) POLA1
SCHEMBL8946831 0.82
SCHEMBL28419764 0.81
SCHEMBL11127408 0.81
SCHEMBL9862349 0.81
SCHEMBL808861 0.77 POLA1 (0.35) POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4442296-A LARVICIDES FMC CORPORATION (US) 1984-04-10 US disclosed
EP-0003336-B1 INSECTICIDAL PERHALOALKYLVINYLCYCLOPROPANECARBOXYLATES FMC Corporation (US) 1984-02-22 EP disclosed
US-4429149-A PYRETHRUM-RELATED INSECTICIDES FMC CORPORATION (US) 1984-01-31 US disclosed
US-4408057-A 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives FMC CORPORATION (US) 1983-10-04 US disclosed
US-4368205-A 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives FMC CORPORATION (US) 1983-01-11 US disclosed
US-4346251-A 4-Substituted-2-indanols FMC CORPORATION (US) 1982-08-24 US disclosed
US-4335252-A A4-PHENYL-Z-INDANYL CYCLOPROPANE CARBOXYLATE FMC CORPORATION (US) 1982-06-15 US disclosed
US-4332815-A Insecticidal perhaloalkylvinylcyclopropanecarboxylates FMC CORPORATION (US) 1982-06-01 US disclosed
US-4263319-A CYCLOPROPYL ESTERS FMC CORPORATION (US) 1981-04-21 US disclosed
US-4243677-A APHIDICIDES; PHOTOSTABILITY FMC CORPORATION (US) 1981-01-06 US disclosed
US-4238505-A HIGH TOXICITY FMC CORPORATION (US) 1980-12-09 US disclosed
US-4235927-A Insecticidal benzylfurylmethyl perhaloalkylvinylcyclopropanecarboxylates FMC CORPORATION (US) 1980-11-25 US disclosed
EP-0003336-A2 Insecticidal perhaloalkylvinylcyclopropanecarboxylates FMC Corporation (US) 1979-08-08 EP disclosed