Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10888977 | 1.00 | KDM4E (0.47) | KDM4EMTNR1AMTNR1BALDH1A1MEN1 | |
| SCHEMBL10884977 | 0.78 | CYP1A2 (0.45) | ALDH1A1MEN1MAPTKMT2AGRIN2D | |
| SCHEMBL11042696 | 0.78 | CYP1A2 (0.45) | ALDH1A1MEN1MAPTKMT2AGRIN2D | |
| SCHEMBL11046190 | 0.77 | KDM4E (0.47) | KDM4EMTNR1AMTNR1BALDH1A1MEN1 | |
| SCHEMBL19398043 | 0.73 | KDM4E (0.48) | KDM4EMTNR1AMTNR1BALDH1A1MEN1 | |
| SCHEMBL19279399 | 0.73 | NR1I2 (0.66) | KDM4EMTNR1AMTNR1BALDH1A1MEN1 | |
| SCHEMBL28257775 | 0.72 | KDM4E (0.57) | KDM4EMTNR1AMTNR1BALDH1A1MEN1 | |
| SCHEMBL11040960 | 0.72 | AKR1C3 (0.45) | KDM4EALDH1A1MAPTGRIN2DGRIN3B | |
| SCHEMBL10886960 | 0.72 | AKR1C3 (0.45) | KDM4EALDH1A1MAPTGRIN2DGRIN3B | |
| SCHEMBL20852695 | 0.72 | NR1I2 (0.53) | KDM4EMTNR1AMTNR1BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473560-A | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |