Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 17/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8234351 | 0.87 | F2RL1 (0.49) | F2RL1TAAR1 | |
| SCHEMBL696724 | 0.82 | F2RL1 (0.60) | F2RL1ADRA2AADRA2BADRA2C | |
| SCHEMBL705511 | 0.81 | ADRA2A (0.53) | F2RL1TAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL2474119 | 0.79 | F2RL1 (0.44) | F2RL1TAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL697817 | 0.79 | F2RL1 (0.53) | F2RL1 | |
| SCHEMBL953691 | 0.79 | F2RL1 (0.51) | F2RL1TAAR1 | |
| SCHEMBL9501488 | 0.77 | F2RL1 (0.46) | F2RL1 | |
| SCHEMBL11293851 | 0.76 | TAAR1 (0.51) | F2RL1TAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL19590813 | 0.73 | F2RL1 (1.00) | F2RL1 | |
| SCHEMBL954072 | 0.73 | F2RL1 (0.58) | F2RL1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024829-B1 | 4-BENZYL- AND 4-BENZOYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Farmos-Yhtyma Oy (FI) | 1984-04-25 | — | — | EP | disclosed |
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | disclosed |
| EP-0064820-A1 | Substituted imidazole and imidazoline derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1982-11-17 | — | — | EP | disclosed |
| EP-0024829-A1 | 4-Benzyl- and 4-benzoylimidazole derivatives, processes for their preparation and pharmaceutical compositions comprising the same | Farmos-Yhtyma Oy (FI) | 1981-03-11 | — | — | EP | disclosed |