⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536494 | 0.92 | — | — | |
| SCHEMBL5054643 | 0.87 | DGKA (0.41) | — | |
| SCHEMBL1060951 | 0.85 | TSHR (0.50) | — | |
| SCHEMBL275122 | 0.85 | TSHR (0.43) | — | |
| SCHEMBL1064431 | 0.82 | DGKA (0.42) | — | |
| SCHEMBL515782 | 0.82 | DGKA (0.42) | — | |
| SCHEMBL9593713 | 0.82 | DGKA (0.42) | — | |
| SCHEMBL9593894 | 0.82 | DGKA (0.42) | — | |
| SCHEMBL2180897 | 0.82 | DGKA (0.42) | — | |
| SCHEMBL1065353 | 0.82 | DGKA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107438428-A | NOVEL SKIN REMODELING STRATEGY | ELC 管理有限责任公司 | 2017-12-05 | — | — | CN | claimed |
| US-11779557-B1 | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics | FLAMEL IRELAND LIMITED (IE) | 2023-10-10 | — | — | US | disclosed |
| US-11135234-B2 | Effective aminoglycoside antibiotic for multidrug-resistant bacteria | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2021-10-05 | — | — | US | disclosed |
| US-20200155582-A1 | EFFECTIVE AMINOGLYCOSIDE ANTIBIOTIC FOR MULTIDRUG-RESISTANT BACTERIA | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2020-05-21 | — | — | US | disclosed |
| US-10617704-B2 | Effective aminoglycoside antibiotic for multidrug-resistant bacteria | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2020-04-14 | — | — | US | disclosed |
| US-10576094-B2 | — | — | 2020-03-03 | — | — | US | disclosed |
| EP-3498723-A1 | NEW EFFECTIVE AMINOGLYCOSIDE ANTIBIOTIC FOR MULTIDRUG-RESISTANT BACTERIA | Microbial Chemistry Research Foundation (JP) | 2019-06-19 | — | — | EP | disclosed |
| US-20180214470-A1 | NEW EFFECTIVE AMINOGLYCOSIDE ANTIBIOTIC FOR MULTIDRUG-RESISTANT BACTERIA | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2018-08-02 | — | — | US | disclosed |
| EP-3330275-A1 | NOVEL AMINOGLYCOSIDE ANTIBIOTIC EFFECTIVE AGAINST MULTIDRUG-RESISTANT BACTERIA | Microbial Chemistry Research Foundation (JP) | 2018-06-06 | — | — | EP | disclosed |
| CN-108026133-A | Effectively antagonize the new aminoglycoside antibiotics of multidrug resistance bacterium | 公益财团法人微生物化学研究会 | 2018-05-11 | — | — | CN | disclosed |
| CN-100457716-C | Novel composition containing acyl group | ASAHI KASEI CHEMICALS CORP (JP) | 2009-02-04 | — | — | CN | disclosed |
| CN-101198309-A | Composition for protection of body surface | ASAHI CHEMICAL CORP (JP) | 2008-06-11 | — | — | CN | disclosed |
| CN-100351107-C | Tire wheel assembly for run-flat tire | YOKOHAMA RUBBER CO LTD (JP) | 2007-11-28 | — | — | CN | disclosed |
| CN-1697738-A | Tire wheel assembly for run-flat tire | YOKOHAMA RUBBER CO LTD (JP) | 2005-11-16 | — | — | CN | disclosed |
| CN-1678566-A | Novel acyl-containing compositions | ASAHI CHEMICAL CORP (JP) | 2005-10-05 | — | — | CN | disclosed |
| CN-1039125-C | Amidinophenylalanine derivatives and process for preparing same and use | REHRINGWERKE AG (DE) | 1998-07-15 | — | — | CN | disclosed |
| CN-1067249-A | Amidinophenylalaninederivatives derivatives and Preparation Method And The Use | BEHRINGWERKE AG (DE) | 1992-12-23 | — | — | CN | disclosed |
| US-4518577-A | Sulfur separation process | SHELL OIL COMPANY (US) | 1985-05-21 | — | — | US | disclosed |
| US-4443424-A | Method of removing hydrogen sulfide from gases utilizing a polyvalent metal chelate solution and electrolytically regenerating the solution | SHELL OIL COMPANY (US) | 1984-04-17 | — | — | US | disclosed |
| US-4443423-A | Method of removing hydrogen sulfide from gases utilizing a polyvalent metal chelate solution and electrolytically regenerating the solution | SHELL OIL COMPANY (US) | 1984-04-17 | — | — | US | disclosed |