Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | TET3 | O43151 | 1/20 | 0.53 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.53 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.53 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.53 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.53 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301027 | 0.87 | KMT2A (0.64) | POLBKMT2ATET3FBXL19CXXC5 | |
| SCHEMBL11046813 | 0.87 | POLB (0.56) | POLBKMT2ATET3FBXL19CXXC5 | |
| SCHEMBL11044409 | 0.85 | POLB (0.50) | POLBKMT2AALDH1A1MEN1CYP3A4 | |
| SCHEMBL1466916 | 0.83 | POLB (0.62) | POLBKMT2ATET3FBXL19CXXC5 | |
| SCHEMBL3443266 | 0.81 | KMT2A (0.61) | POLBKMT2ATET3FBXL19CXXC5 | |
| SCHEMBL503291 | 0.81 | KMT2A (0.65) | KMT2ATET3FBXL19CXXC5TET1 | |
| SCHEMBL735386 | 0.81 | AKR1C1 (0.61) | POLBKMT2ATET3FBXL19CXXC5 | |
| SCHEMBL3219496 | 0.80 | APP (0.50) | KMT2ACYP3A4CYP2C19 | |
| SCHEMBL21874196 | 0.80 | KMT2A (0.57) | POLBKMT2ATET3FBXL19CXXC5 | |
| SCHEMBL21874269 | 0.80 | KMT2A (0.63) | KMT2ATET3FBXL19CXXC5TET1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035902-B1 | 1-(4-ARYL-CYCLOHEXYL)PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-31 | — | — | EP | disclosed |
| US-4329353-A | ANTIEMETIC AND NEUROLEPTIC AGENTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1982-05-11 | — | — | US | disclosed |
| EP-0035902-A1 | 1-(4-Aryl-cyclohexyl)piperidine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1981-09-16 | — | — | EP | disclosed |