Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.58 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.51 |
| ▸ | MEN1 | O00255 | 11/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27660778 | 0.87 | GAA (0.57) | GAAMAPTMCL1SMN1; SMN2CYP1A2 | |
| SCHEMBL29709862 | 0.85 | KMT2A (0.56) | GAAMAPTMCL1SMN1; SMN2CYP1A2 | |
| SCHEMBL5337037 | 0.85 | KMT2A (0.56) | GAAMAPTMCL1SMN1; SMN2CYP1A2 | |
| SCHEMBL18338668 | 0.83 | GAA (0.50) | GAAMAPTMCL1SMN1; SMN2CYP1A2 | |
| SCHEMBL18338669 | 0.83 | GAA (0.50) | GAAMAPTMCL1SMN1; SMN2CYP1A2 | |
| SCHEMBL18338670 | 0.77 | GAA (0.51) | GAAMAPTMCL1SMN1; SMN2CYP1A2 | |
| SCHEMBL6527367 | 0.75 | GAA (0.65) | GAAMAPTMCL1SMN1; SMN2CYP1A2 | |
| Methylglyoxal SCHEMBL6013425 | 0.75 | GAA (0.51) | GAAMAPTMCL1SMN1; SMN2CYP1A2 | |
| SCHEMBL8485540 | 0.74 | GAA (1.00) | GAAMAPTMCL1SMN1; SMN2CYP1A2 | |
| SCHEMBL1268566 | 0.74 | GAA (0.62) | GAAMAPTMCL1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59048097-A | — | — | None | — | — | JP | disclosed |
| JP-S5948097-A | FRACTIONATION AND DETERMINATION OF POLYAMIDE AND ACETYL-POLYAMINE | AMANO PHARMACEUT CO LTD | 1984-03-19 | — | — | JP | disclosed |