Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.65 |
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.59 |
| ▸ | MEN1 | O00255 | 10/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.59 |
| ▸ | CCR6 | P51684 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15018298 | 0.82 | KMT2A (0.77) | GAAMAPTMCL1KMT2AMEN1 | |
| SCHEMBL8485540 | 0.78 | GAA (1.00) | GAAMAPTMCL1KMT2AMEN1 | |
| SCHEMBL1773293 | 0.78 | GAA (0.62) | GAAMAPTMCL1KMT2AMEN1 | |
| SCHEMBL1268566 | 0.78 | GAA (0.62) | GAAMAPTMCL1KMT2AMEN1 | |
| SCHEMBL315396 | 0.78 | GAA (0.62) | GAAMAPTMCL1KMT2AMEN1 | |
| SCHEMBL4197315 | 0.78 | GAA (0.62) | GAAMAPTMCL1KMT2AMEN1 | |
| SCHEMBL15040701 | 0.78 | GAA (0.62) | GAAMAPTMCL1KMT2AMEN1 | |
| SCHEMBL27660778 | 0.78 | GAA (0.57) | GAAMAPTMCL1KMT2AMEN1 | |
| SCHEMBL11844059 | 0.78 | GAA (0.69) | GAAMAPTMCL1KMT2AMEN1 | |
| SCHEMBL11874703 | 0.78 | KMT2A (0.74) | GAAMAPTMCL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239804-A1 | Method for improved chemical synthesis of guanidinium alkaloids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2005-10-27 | — | — | US | disclosed |
| CN-1487942-A | Hexahydropyrrolo [1,2-c] pyrimidines as antiviral, antifungal and/or antitumor agents | �Ϻ���ͨ��ѧ | 2004-04-07 | — | — | CN | disclosed |
| EP-1204666-A1 | HEXAHYDROPYRROLO[1,2-C]PYRIMIDINES AS ANTIVIRAL, ANTIFUNGAL AND/OR ANTITUMOR AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-05-15 | — | — | EP | disclosed |
| US-20010020345-A1 | Gasoline additive for direct injection gasoline engine | NIPPON MITSUBISHI OIL CORPORATION | 2001-09-13 | — | — | US | disclosed |
| EP-1122295-A1 | GASOLINE ADDITIVE FOR DIRECT-INJECTION GASOLINE ENGINE | Nippon Mitsubishi Oil Corporation (JP) | 2001-08-08 | — | — | EP | disclosed |
| WO-2001000626-A1 | HEXAHYDROPYRROLO[1,2-C]PYRIMIDINES AS ANTIVIRAL, ANTIFUNGAL AND/OR ANTITUMOR AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-01-04 | — | — | WO | disclosed |
| US-5928393-A | ESTERIFIED, ALKOXYLATED TERTIARY AMINE COMPOUND; DETERGENT ANTISLUDGE/ANTIDEPOSIT AGENT FOR INTERNAL COMBUSTION ENGINES | NIPPON OIL CO., LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0819753-A1 | Fuel additive | NIPPON OIL CO. LTD. (JP) | 1998-01-21 | — | — | EP | disclosed |
| US-4328223-A | 2-Amino-3a,4,5,6-tetrahydro-perimidine derivatives and their medicinal use in combatting circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-04 | — | — | US | disclosed |
| EP-0004904-B1 | 2-AMINO-3A,4,5,6-TETRAHYDROPERIMIDINE DERIVATIVES, MEDICAMENTS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1981-07-29 | — | — | EP | disclosed |
| EP-0004904-A1 | 2-Amino-3a,4,5,6-tetrahydroperimidine derivatives, medicaments containing them and process for their preparation | BAYER AG (DE) | 1979-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239804-A1 | Method for improved chemical synthesis of guanidinium alkaloids | PAICS, TYMS, IMPDH1 | GAA 902/4885MAPT 3490/4885MCL1 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.