SCHEMBL11046807

SCHEMBL11046807

C=C[C](C)C(C)CC=C(C)C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
ALOX15 P16050 2/20 0.31
ALDH1A1 P00352 1/20 0.31
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11143715 0.76 TSHR (0.37) TSHRALOX15GRIK1GRIK2
SCHEMBL735056 0.75 TSHR (0.34) TSHRALOX15ALDH1A1GRIK1GRIK2
Bromide SCHEMBL28859977 0.73 TSHR (0.33) TSHRALOX15ALDH1A1GRIK1GRIK2
SCHEMBL11794760 0.72
SCHEMBL10878954 0.70 GRIK1 (0.41) TSHRALOX15ALDH1A1GRIK1GRIK2
SCHEMBL2440971 0.70 GRIK1 (0.41) TSHRALOX15ALDH1A1GRIK1GRIK2
SCHEMBL2048567 0.70
SCHEMBL11436935 0.70 GRIK1 (0.34) ALOX15GRIK1GRIK2
SCHEMBL8391852 0.69
SCHEMBL132111 0.68 GRIK1 (0.48) ALDH1A1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4447365-A ORGANOLEPTIC AGENT INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1984-05-08 US disclosed
US-4390463-A Process for augmenting or enhancing the aroma of perfume compositions and colognes utilizing alkyl, aralkyl, and bicycloalkyl methyl carbonates INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1983-06-28 US disclosed