Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735056 | 0.97 | TSHR (0.34) | TSHRALDH1A1ALOX15GRIK1GRIK2 | |
| SCHEMBL11833363 | 0.78 | — | — | |
| SCHEMBL11833356 | 0.78 | — | — | |
| SCHEMBL22454730 | 0.76 | — | — | |
| SCHEMBL23467259 | 0.75 | — | — | |
| SCHEMBL1135743 | 0.74 | — | — | |
| SCHEMBL529942 | 0.74 | — | — | |
| SCHEMBL21065790 | 0.73 | ALOX15 (0.50) | TSHRALDH1A1ALOX15 | |
| SCHEMBL11046807 | 0.73 | TSHR (0.37) | TSHRALDH1A1ALOX15GRIK1GRIK2 | |
| SCHEMBL9814233 | 0.73 | FNTA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026005-A | Homoallylic halide composition and method for preserving homoallylic halide | 株式会社可乐丽 | 2018-05-11 | — | — | CN | disclosed |