Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13253935 | 1.00 | OPRM1 (0.59) | OPRM1SLC6A3SLC6A4OPRL1PDE4B | |
| SCHEMBL10529109 | 0.85 | OPRM1 (0.71) | OPRM1SLC6A3SLC6A4OPRL1SLC6A2 | |
| SCHEMBL13253932 | 0.85 | OPRM1 (0.59) | OPRM1SLC6A3SLC6A4OPRL1SLC6A2 | |
| SCHEMBL15863283 | 0.82 | OPRM1 (0.68) | OPRM1SLC6A3SLC6A4OPRL1SLC6A2 | |
| SCHEMBL7382986 | 0.82 | OPRM1 (0.68) | OPRM1SLC6A3SLC6A4OPRL1SLC6A2 | |
| SCHEMBL3518560 | 0.82 | OPRM1 (0.63) | OPRM1SLC6A3SLC6A4OPRL1SLC6A2 | |
| SCHEMBL3518561 | 0.82 | OPRM1 (0.63) | OPRM1SLC6A3SLC6A4OPRL1SLC6A2 | |
| SCHEMBL3518556 | 0.82 | OPRM1 (0.63) | OPRM1SLC6A3SLC6A4OPRL1SLC6A2 | |
| SCHEMBL3519309 | 0.81 | OPRM1 (0.66) | OPRM1SLC6A3SLC6A4OPRL1SLC6A2 | |
| SCHEMBL1558648 | 0.80 | MEN1 (0.51) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035902-B1 | 1-(4-ARYL-CYCLOHEXYL)PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-31 | — | — | EP | disclosed |