Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045018 | 0.89 | PDE4A (0.40) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11049626 | 0.87 | PDE4A (0.41) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11042976 | 0.87 | SLC29A1 (0.49) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11025105 | 0.86 | SLC29A1 (0.47) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11026053 | 0.84 | SLC29A1 (0.50) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11041201 | 0.84 | SLC29A1 (0.52) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11024479 | 0.84 | KDM4E (0.32) | KDM4E | |
| SCHEMBL11032117 | 0.84 | SLC29A1 (0.52) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11051919 | 0.83 | SLC29A1 (0.40) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11028323 | 0.83 | SLC29A1 (0.45) | SLC29A1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478833-A | ANTICOAGULANTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0055444-A2 | Trisubstituted pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-07-07 | — | — | EP | disclosed |