⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24318705 | 0.93 | CHRNB2 (0.50) | — | |
| SCHEMBL9587596 | 0.93 | CHRNB2 (0.50) | — | |
| SCHEMBL19607953 | 0.93 | CHRNB2 (0.50) | — | |
| SCHEMBL24452809 | 0.93 | CHRNB2 (0.50) | — | |
| SCHEMBL16541245 | 0.89 | CHRNB2 (0.65) | — | |
| SCHEMBL25150433 | 0.86 | EPHX1 (0.67) | — | |
| SCHEMBL22146554 | 0.86 | EPHX1 (0.61) | — | |
| SCHEMBL19607946 | 0.84 | EPHX1 (0.70) | — | |
| SCHEMBL20317421 | 0.83 | EPHX1 (0.58) | — | |
| SCHEMBL16640913 | 0.82 | CHRNB2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025922-A1 | TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS | MERCK HEALTHCARE KGAA (DE) | 2024-01-25 | — | — | US | disclosed |
| US-11859099-B2 | Amphiphilic siloxane-polyurethane fouling-release coatings and uses thereof | NDSU RESEARCH FOUNDATION (US) | 2024-01-02 | — | — | US | disclosed |
| US-11859099-B2 | Amphiphilic siloxane-polyurethane fouling-release coatings and uses thereof | NDSU RESEARCH FOUNDATION (US) | 2024-01-02 | — | — | US | disclosed |
| WO-2023230609-A1 | HETEROCYCLIC PAD4 INHIBITORS | CELGENE CORPORATION (US) | 2023-11-30 | — | — | WO | disclosed |
| US-11827804-B2 | Curable coating compositions containing glycidyl carbamate resins and amphiphilic glycidyl-carbamate-functional prepolymers having fouling-release and anti-icing properties | NDSU RESEARCH FOUNDATION (US) | 2023-11-28 | — | — | US | disclosed |
| WO-2023220541-A1 | TETRAHYDROPYRIDO[3,4-D]PYRIMIDINES COMPOUNDS AS HPK1 INHIBITORS | MERCK PATENT GMBH (DE) | 2023-11-16 | — | — | WO | disclosed |
| US-20230167100-A1 | QUINOLINE COMPOUNDS AND COMPOSITIONS FOR INHIBITING EZH2 | NOVARTIS AG (CH) | 2023-06-01 | — | — | US | disclosed |
| CN-111349185-B | Solid catalyst for propylene polymerization and method for producing block copolymer using the same | 韩华道达尔能源有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-20220280509-A1 | AZA-QUINOLINE COMPOUNDS AND USES THEREOF | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2022-09-08 | — | — | US | disclosed |
| US-11427657-B2 | Solid catalyst for propylene polymerization and method of producing block copolymer using the same | HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) | 2022-08-30 | — | — | US | disclosed |
| US-20100199361-A1 | Role of Proteoglycans in Drug Dependence | Sanna, Pietro Paolo (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100168195-A1 | DERIVATIVES AND ANALOGS OF CHROMAN AS FUNCTIONALLY SELECTIVE ALPHA2C ADRENORECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. | 2010-07-01 | — | — | US | disclosed |
| EP-2119720-A1 | NOVEL VINBLASTINE DERIVATIVES, THEIR PREPARATION, USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAID DERIVATIVES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2009-11-18 | — | — | EP | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-20090012035-A1 | DENDRIMER CONJUGATES OF AGONISTS AND ANTAGONISTS OF THE GPCR SUPERFAMILY | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPA (US) | 2009-01-08 | — | — | US | disclosed |
| US-20080262076-A1 | Novel Tetracyclic Tetrahydrofuran Derivatives Containing Cyclic Amine Side Chain | JANSSEN PHARMACEUTICA, NV (BE) | 2008-10-23 | — | — | US | disclosed |
| US-20080262076-A1 | Novel Tetracyclic Tetrahydrofuran Derivatives Containing Cyclic Amine Side Chain | JANSSEN PHARMACEUTICA, NV (BE) | 2008-10-23 | — | — | US | disclosed |
| EP-1910358-A2 | HETEROCYCLIC JANUS KINASE 3 INHIBITORS | Astellas Pharma Inc. (JP) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007007919-A2 | HETEROCYCLIC JANUS KINASE 3 INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2007-01-18 | — | — | WO | disclosed |
| US-4479002-A | CHEMICAL INTERMEDIATES FOR INSECTICIDES, PESTICIDES | UNION CARBIDE CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |