Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976051 | 0.78 | CHRNA7 (0.42) | CXCL12HPGDHTTMEN1KMT2A | |
| SCHEMBL10975099 | 0.78 | HPGD (0.41) | CXCL12HPGDHTTSIRT1MEN1 | |
| SCHEMBL10978019 | 0.78 | HPGD (0.41) | CXCL12HPGDHTTSIRT1MEN1 | |
| SCHEMBL2129184 | 0.77 | HSD17B10 (0.46) | CXCL12HPGDHTTSIRT1ALDH1A1 | |
| SCHEMBL5888020 | 0.73 | CXCL12 (0.40) | CXCL12HPGDHTTSIRT1ALDH1A1 | |
| SCHEMBL5609334 | 0.71 | CXCL12 (0.39) | CXCL12HPGDHTTSIRT1ALDH1A1 | |
| SCHEMBL11401729 | 0.71 | NR1H2 (0.50) | HPGDNR1H2MEN1KMT2AALDH1A1 | |
| Diphenylsulfane SCHEMBL27847104 | 0.71 | CA12 (0.65) | HPGDSIRT1NR1H2MEN1KMT2A | |
| Diphenylsulfane SCHEMBL11742482 | 0.71 | CA12 (0.65) | HPGDSIRT1NR1H2MEN1KMT2A | |
| Diphenylsulfane SCHEMBL11499754 | 0.69 | NR1H2 (0.78) | HPGDNR1H2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486422-A | SYSTEMIC | THE DOW CHEMICAL COMPANY (US) | 1984-12-04 | — | — | US | disclosed |