Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044864 | 0.93 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11047395 | 0.92 | ALDH1A1 (0.45) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL26761188 | 0.91 | ALDH1A1 (0.53) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11122289 | 0.90 | ALDH1A1 (0.47) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10680118 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11043191 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11040338 | 0.88 | MAPT (0.46) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL6459389 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11050852 | 0.88 | ALDH1A1 (0.45) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11341411 | 0.87 | MAPT (0.45) | ALDH1A1KDM4ENPC1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044209-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | claimed |
| US-4348220-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | claimed |
| EP-0044209-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | disclosed |
| US-4424377-A | HERBICIDES | E. I. DU PONT DE NEMOURS & CO. (US) | 1984-01-03 | — | — | US | disclosed |
| US-4348220-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0044209-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-20 | — | — | EP | disclosed |