Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404391 | 0.93 | MEN1 (0.69) | MAPTMEN1KMT2ATDP1CHRNB2 | |
| SCHEMBL6753107 | 0.85 | ATM (0.66) | MAPTMEN1KMT2ATDP1KDM4E | |
| Carbaril SCHEMBL8343919 | 0.82 | ALDH1A1 (0.70) | MAPTMEN1KMT2ATDP1KDM4E | |
| SCHEMBL29691646 | 0.82 | MEN1 (0.52) | MAPTMEN1KMT2ATDP1KDM4E | |
| SCHEMBL5999001 | 0.81 | NQO2 (0.62) | MAPTMEN1KMT2ATDP1KDM4E | |
| SCHEMBL6753141 | 0.81 | ALDH1A1 (0.60) | MAPTMEN1KMT2ATDP1KDM4E | |
| SCHEMBL22323341 | 0.81 | MEN1 (0.66) | MAPTMEN1KMT2ATDP1CHRNB2 | |
| SCHEMBL4432071 | 0.80 | KMT2A (0.65) | MAPTMEN1KMT2ATDP1KDM4E | |
| SCHEMBL16899289 | 0.80 | KDM4E (0.59) | MAPTMEN1KMT2ATDP1KDM4E | |
| SCHEMBL16899286 | 0.80 | KDM4E (0.59) | MAPTMEN1KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120360-A1 | Solutions of 1-naphthylmethylcarbamate | S.C. JOHNSON & SON, INC. (US) | 1984-10-03 | — | — | EP | claimed |
| EP-0120360-A1 | Solutions of 1-naphthylmethylcarbamate | S.C. JOHNSON & SON, INC. (US) | 1984-10-03 | — | — | EP | disclosed |