Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 3/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.46 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26926736 | 0.90 | APP (0.45) | AKR1B10AKR1B1LMNAALDH1A1HDAC3 | |
| SCHEMBL10906541 | 0.88 | POLB (0.44) | AKR1B10AKR1B1LMNAALDH1A1HDAC3 | |
| SCHEMBL27695239 | 0.87 | LMNA (0.49) | AKR1B10AKR1B1LMNAALDH1A1HDAC3 | |
| SCHEMBL10906128 | 0.86 | TSHR (0.44) | AKR1B10AKR1B1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10771896 | 0.86 | TDP1 (0.46) | ALDH1A1HDAC3GLATDP1BCHE | |
| SCHEMBL27787924 | 0.86 | POLB (0.51) | AKR1B10AKR1B1LMNAALDH1A1HDAC3 | |
| SCHEMBL5843377 | 0.86 | TDP1 (0.44) | AKR1B10AKR1B1LMNAALDH1A1HDAC3 | |
| SCHEMBL10906572 | 0.84 | TSHR (0.53) | LMNAALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL10906553 | 0.84 | TSHR (0.49) | AKR1B10AKR1B1HDAC3KMT2AMEN1 | |
| SCHEMBL29394 | 0.84 | KDM4E (0.53) | AKR1B10AKR1B1ALDH1A1HDAC3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085795-B | Polystyrene acrylic acid-2-hydroxyethyl ester and synthetic method and application thereof | 中国石油天然气股份有限公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-106459352-A | Retroreflective articles with wash durable bead bond layers | 3M创新有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105085795-A | Polystyrene acrylic acid-2-hydroxyethyl ester and synthetic method and application thereof | PETROCHINA CO LTD | 2015-11-25 | — | — | CN | disclosed |
| US-4438245-A | FOR LIGHT SENSITIVE ELEMENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-03-20 | — | — | US | disclosed |